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Anti tnf drugs - humira or enbrel???? Options
LynW
#21 Posted : Thursday, April 15, 2010 9:10:47 PM Quote
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Joined: 12/4/2009
Posts: 2,127
Location: Thornton Cleveleys
Hello Nicki (making an assumption in your name, apologies if I'm wrong!!)

Welcome to the forum! I'm Lyn, married with four children and living in Lancashire. I have had RA for 22 years and run the gamut of medication and surgical procedures. I'm currently on Enbrel, Methotrexate, Prednisolne and Naproxen and a cupboard full of additional bits and pieces to keep things working!

Each of the anti-tnfs has its own pros and cons and you will find, on the forum, lots of personal experiences about each of the drugs so worth having a search through. I have had Infliximab infusions and they were like a miracle cure! I have never felt so well. Unfortunately the efficacy didn't last and I was changed to Enbrel. This too has been good in combination with Methotrexate. The injections are easy and nothing to worry about and only a slight soreness as the needle goes in. I can actually do it without feeling anything but its finding the spot!! Benefit can be felt from Enbrel after about 6 weeks but it varies with individuals. Infliximab was immediate! There can be side effects but again everyone is different. The drugs and side effects are carefully monitored by regular blood tests, two weekly to start with until things settle, then monthly. You will also have six monthly DAS checks to ensure the drugs are working and inflammation levels.

Your consultant may have their own preference of drug that they would like you to have. If you can't come to a decision it would be worth asking their advice as they will know from experience which drug will be most suitable for your needs. They each work in a slightly different way.

Any more questions please fire away. Everyone here is very helpful and friendly so you are in the right place for help and support. Looking forward to getting to know you better,

Lyn x
My son, Ian, completed the BUPA Great North Run on 15th September running for the National Rheumatoid Arthritis Society (NRAS). You can read his story at http://www.justgiving.com/ianlukewilson

smith-j
#22 Posted : Friday, April 16, 2010 1:01:01 PM Quote
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Joined: 12/3/2009
Posts: 714
Hi

I was approved for anti-tnf's two month's ago. I was given all the literature on all three options and told to go away and make a choice. I went to my GP for his help and all he could tell me was how much it costRollEyes . So I looked at the least side effects and chose Humira. When I saw my Rheumy Nurse to tell her what I had chosen, she pursed her lips and said ........... "well actually the Consultant prefers Enbrel". So being the good girl I am, and not wanting to upset my Consultant, I chose the Enbrel.

I started the Enbrel five weeks ago by weekly self-injection with an epi pen. I was very nervous but they sent out a nurse for the first injection to show me how to do it and she gave me top scores and said I was brilliant and to get on with it. To be honest it does hurt a little bit but gets easier each time. Unfortunately I have failed on the Enbrel. I have developed a rash and they have told me to stop it as they think I am allergic to it. If I am, then guess what, I will be moving onto the Humira BigGrin Unfortunately I have just learnt that I need major surgery over the next month so will not be going any further with the anti-tnfs until I have recovered from the surgery.

It is a mine field when deciding what to do but I think at the end of the day it is down to your own gut reaction (pardon the pun).

You will have lots of support from this forum and someone will always be able to answer your questions.

Take care

Jackie
xx
lyn2
#23 Posted : Friday, April 16, 2010 3:54:01 PM Quote
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Joined: 12/10/2009
Posts: 653
Location: Notts
I now inject Enbrel every week, before that I was on humira. It's easy to learn how to inject, usually a nurse will come to your house to show you, and will probably come back to watch you inject yourself. It doesn't hurt putting in the injection but the liquid does sting abit, but only for seconds.

I don't seem to get any side effects, nothing out of the ordinary anyway. It can take a few weeks to feel the full benefit.

Hope all goes well for you.

Lyn
minxnicki
#24 Posted : Monday, April 19, 2010 3:06:01 PM Quote
Rank: Newbie

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Joined: 4/15/2010
Posts: 3
Thanks for your help Lyn, Jackie & Lyn! I will continue to do my research! I noticed NRAS are launching a "Guide to Biologics" on Wednesday so I think that may be what I need! Nicki x
Damned76
#25 Posted : Monday, April 26, 2010 7:49:34 PM Quote
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Joined: 12/3/2009
Posts: 1,081
Hi Nina, I just wondered if you had started on the Humira and how you were doing?

I've just been for my 2nd assessment today (not sure if I qualify as nurse couldn't get results from rheumy ward where 1st assessment was done). Have been offered choice of infliximab, cimza, enbrel and humira but think I will ask for humira like you.

I hope it's going well.

Julie
Funkyhugg
#26 Posted : Monday, April 26, 2010 8:44:02 PM Quote
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Joined: 12/23/2009
Posts: 10
Location: Planet F1
Ive been on Humira since June 2006 and it totally changed my life. No one would know I had RA if it wasnt for routine hospital appointments I have to attend.

It doesnt work for everyone, (no medicine does) but good luck.
BigGrin
Mmmmm, fuzzy.....
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